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Osteoarthritis is the most common joint disease worldwide, affecting an estimated 10% of men and 18% of women over 60 years of age. The incidence and prevalence of osteoarthritis depends on the definition used, such as symptomatic, radiographic, self-reported, or doctor-diagnosed; it can be described pathologically, radiographically, or clinically. It should be noted that not everyone with radiographic OA is symptomatic. Due to the various definitions of OA that are used, the reported prevalence and incidence rates vary across studies. In general, prevalence for symptomatic OA tends to be lower than radiographic OA as its presence is defined by a combination of symptoms such as pain and stiffness in addition to radiographic features.