Read Aloud the Text Content

This audio was created by Woord's Text to Speech service by content creators from all around the world.

Text Content or SSML code:

Acute lymphoblastic leukemia is a blood related disease. For a primary data , researchers would have to go out and take blood samples from individuals for examination. Then the examine samples would help them to generate a gene expressed data set for the study. But for the purpose of our study, we would use a secondary. We took the data from a public gene expression repository. The data set was a matrix : genes representing the rows and samples representing the columns. We then perform filtering using a threshold to remove unexpressed genes from the data set. Our dataset has fpkm values : which are skewed so we then perform a log transform to scale the data to a single unit We then perform a pairwise comparison test for the groups Our null hypothesis is for each gene, n group has no significant difference in the means of the n groups Alternative hypothesis is for each gene , there’s a significant difference in the means of the groups For pairwise comparison test, the student t test is the best to use according to literature.