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Let us see what is a “research question”.... A research question is usually the first step in any research project. Basically, it is the primary interrogation point of research and it sets the pace of research project. The 1st step in a systematic review is to Formulate a clear, well-defined research question of appropriate scope. Research question lie at the core of systematic investigation and this is because recording accurate research outcomes is tied to asking the right questions. Asking the right questions when conducting research can help researcher collect relevant and insightful information that ultimately influences the research positively. Typically, a research question focuses on the research, determines the methodology and hypothesis, and guides all stages of inquiry, analysis, and reporting. With the right research questions, researcher will be able to gather useful information for the investigation.