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Have you ever experienced a changing weather effect on your health? The answer is not that much simple, scientists found that changing weather can have a long time adverse effect on human body. To examine this scenario, We proposed Destination Earth project. The purpose is Sentinel-3 , TERRA / AQUA and EUMETSAT satellites will collect land surface temperature, vertical temperature and cloud cover data. While, Health data was collected from D,H,I.R. A novel Holistic approach is developed to process the datasets and generate forecasting. The expected output of this project are , The project can be extend in future by adding some more weather parameters and analyze their impact on human health. This project not only discloses the crucial effects of weathers but also help us to improve our health facilities……..