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Currently, Multi-omics approaches have become popular in the study of a wide range of biological domains, with multi-omics datasets now commonly obtained by individual investigators and large organizations. Moreover, the number and diversity of measured omics modalities have also increased, with former studies combining at most two or three omics platforms, and more recently, genomics, transcriptomics, methyl-omics, chromatin accessibility, proteomics, metabolomics often combined in a single study.