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Meanwhile, the “diseases of civilization,” as discussed by Eaton and Konner in the January 31, 1985 New England Journal of Medicine and contrasted with the healthful pre-farming diets, underline the joyless, sickly world of chronic maladjustment we inhabit as prey of the manufacturers of medicine, cosmetics, and fabricated food. Domestication reaches new heights of the pathological in genetic food engineering, with new types of animals in the offing as well as contrived microorganisms and plants. Logically, humanity itself will also become a domesticate of this order as the world of production processes us as much as it degrades and deforms every other natural system. The project of subduing nature, begun and carried through by agriculture, has assumed gigantic proportions. The “success” of civilization’s progress, a success earlier humanity never wanted, tastes more and more like ashes. James Serpell summed it up this way: “In short we appear to have reached the end of the line. We cannot expand; we seem unable to intensify production without wreaking further havoc, and the planet is fast becoming a wasteland.” Awareness of the consequences of civilization and its history seems to be making itself felt in the twenty-first century. This awareness may even come to rival the overall sense of civilization’s inevitability. It is showing up in the academic literature, for example. In the journal Nature (07 January 2016), S. Kathleen Lyons et al. point out that plant and animal communities were stable and healthy for 300 million years, before they were disrupted 6,000 years ago by the spread of agriculture. John R. Schramski et al. (Nature, 04 May 2015) describe the earth reaching an end point, a battery running out of dischargeable energy. Research by Anthony D. Barnosky et al. (Nature, 04 May 2012) contemplates collapse, a global ecosystem approaching a tipping point. Jared Diamond termed the initiation of agriculture “a catastrophe from which we have never recovered.” Agriculture has been and remains a “catastrophe” at all levels, the one which underpins the entire material and spiritual culture of alienation now destroying us. Liberation is impossible without its dissolution.