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The monitoring in "in operation" condition (active air sampling) must be carried out in accordance with WI 20012734 (BQCEM07) and 20034131 (BQCEM57) and provides for the sampling of Room P108, including the surface of the handle of the Minicapt Mobile 50M used inside the filling machine (Ref. WI 20034105 / BQCEM56). During the sampling operations, the Operators present in the aseptic area they must take care to move slowly in order to avoid turbulence that could disturb the environmental conditions.