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What does a woman do if her husband irritates her? Perhaps offer him the cold shoulder, force him to sleep on the sofa, deny his love for a week or two—or even kill him? There are tales of women whose final nerves broke and they had to say farewell to Dear Old Hubby, like something out of "Cell Block Tango." Rather than using knives, weapons, a hitman, or dragging him down a flight of stairs, these Femme Fatales chose their poison. Though not all famous stories of women poisoning their husbands end in death, I believe the husband understood the point in the end. Either he really "had it coming," or there was a more sick and sadistic scheme in the works. Here are the top ten wives who poisoned their husbands.