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Next, I’m going to explain results we have obtained. The graph represents the FICI index of different fungal strains. In this study, we tested yeasts like Candida glabrata, auris and albicans, and filamentous fungi like Aspergillus fumigattus, Scedosporuim apiospermum and Fusaruim solani. Red dashed line denotes the cutoff FIC index of 0.5 for synergistic interaction. As can be seen in the graph, F46 combined with VRC showed synergistic effect against 8/19 (represents more than 42%) strains tested, with the effect being observed mainly in 3/4 (75%) of the C. albicans strains. While in C. auris and A fumigatus strains the combination was synergistic in two strains tested. In the case of C. glabrata and F. solani synergism was only observed in one strain. No synergy was observed in Solani strains. The combination of F46 and VRC had higher synergistic effect compared to other combinations. F46 + PSC had effect against 7/19 (36.8%) strains tested. Half (50%) of the C. albicans and C. auris strains shown synergistic effect. The combination had no synergistic effects on Scedosporium apiospermum and neither on two Aspegillus strains out of three totals tested. Finally, no synergistic effect has been observed when combined F42 with FCZ, drug interaction shows indifference in most strains. In the next seminar, I hope to present you results on another flavone compound.