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5. A sac with no embryo and an MSD <12 mm on initial scan that fails to double in size on a scan ≥14 days later. 6. Sac with no embryo and an MSD ≥12 mm on initial scan with no embryo heart activity on a scan ≥7 days later . 7. Embryo (irrespective of crown-rump length) without cardiac activity on initial scan and on repeat scan ≥7 days later . 8. Cessation of a previously documented cardiac activity of embryo (irrespective of crown-rump length)