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There are four inherent risks in creating partnerships. The main one is the Impedance mismatch: when a big company joins a start-up, there is a big discrepancy between the commitment that each entity puts into the relationship. What for a start-up represents a unique opportunity for growth and business development, for the company it is just another partnership, less essential to its success. It’s also necessary to take into account that the start-up’s negotiating power is null against a major company which may lead to its subjugation and dependency upon the partnership. Misalignment between the start-up’s and the company’s objectives might also be a potential risk. The start-up may have in mind a given, declared objective with the company, while the actual goal of the company is personal, such as promoting someone or just an item on the task list. Another possible scenario is that the company is trying to prevent the growth of the start-up and to have access to the technology that it is developing. The third risk is that, when allied with a large company, the start-up may lose the visibility of its product and feather under the name of the larger company. It is, therefore, necessary to ensure that the name of the start-up is properly included and advertised in the product and communicated to the public. There is no need for the company to marketeer the start-up’s product under its name. Finally, it's crucial to be aware that exclusive contracts are often used by large companies to control start-ups and have exclusive access to their technology, so it's necessary to avoid these contracts, thus avoiding dependency on a single major partner. In Summary, partnerships are something indispensable for a start-up but it is necessary to take some losses to avoid failed partnerships. For this, it is essential to reflect on the different types of partnerships that are desired throughout the business life cycle. In the first phase, it may not be necessary to have large companies as partners, as the clients meant to be reached out are not the mainstream audience that is generally targeted when the product is matured. Understanding the pros and cons of partnerships and not deluding with the importance that we have for the life of a large company are important considerations when a partnership is being created. Finally, bearing in mind that partnerships are not constant over time and that today´s partners might not be tomorrow´s leads to the conclusion that it is necessary to maintain a good relationship with all potential partners.